Biophotonics-Driven Advances in Biomedical Imaging: Evolving Techniques, Ongoing Challenges, and Forward-Looking Strategies
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Abstract
Biophotonics, positioned at the intersection of photonics and life sciences, has rapidly transformed biomedical imaging by enabling minimally invasive visualization of biological structures and functions across molecular, cellular, and tissue scales. While individual imaging technologies such as Raman spectroscopy, optical coherence tomography, fluorescence‑lifetime imaging, and multiphoton microscopy have been extensively studied, their collective evolution reveals a deeper set of transitions that continues to redefine biomedical diagnostics. This paper highlights these shifts through a multi‑paradigm framework that moves from purely structural visualization to function‑resolved and computationally enhanced imaging. Beyond summarizing established principles and operational trade‑offs, the paper synthesizes emerging approaches aimed at surpassing performance barriers associated with resolution, penetration depth, and space‑bandwidth limits. Special emphasis is placed on recent advances in computational imaging, micro‑endomicroscopy, and next‑generation biophotonic probes that integrate artificial intelligence, novel nanomaterials, and biologically embedded light sources. By contextualizing these developments within a broader trajectory of convergence between optics, computation, and material science, this work provides an updated and forward‑looking perspective on how biophotonics is shaping the next phase of translational imaging and precision‑medicine applications.
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Publication Details
- Type of Publication:
- Conference Name: 2026 IEEE 2nd International Conference on Quantum Photonics, Artificial Intelligence & Networking
- Date of Conference: 16/04/2026 - 16/04/2026
- Venue: CUET, Chattogram, Bangladesh
- Organizer: QPAIN