Molecular Biology
This research group is dedicated to investigating the genetic and molecular foundations of human diseases, with the goal of identifying biomarkers, elucidating disease mechanisms, and enhancing therapeutic outcomes. The group is actively involved in pharmacogenomics and pharmacogenetics research, examining how genetic variations influence individual drug responses. Their work encompasses a range of critical health conditions, including various cancers, HIV, tuberculosis (TB), psoriasis, autism spectrum disorder, thalassemia, dengue, and COVID-19. Utilizing advanced molecular biology techniques—such as PCR, gene sequencing, and bioinformatics analyses—the team aims to uncover genetic mutations and polymorphisms associated with disease susceptibility and treatment efficacy. Ultimately, this research supports the advancement of personalized medicine in Bangladesh, promoting safer and more effective therapies tailored to individual genetic profiles.INTEREST(S)
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VISION
The vision of this Research Group is to become an internationally recognized center of excellence in molecular and genetic research, driving innovation in disease prevention, diagnosis, and treatment. Through the integration of advanced molecular tools, interdisciplinary collaboration, and translational research, the group aims to contribute meaningfully to the global advancement of precision medicine—ensuring that every patient receives safe, effective, and personalized healthcare tailored to their genetic profile.
MISSION
The mission of this Research Group is to advance scientific understanding of the genetic and molecular mechanisms underlying human diseases. Through innovative research in molecular biology, pharmacogenomics, and pharmacogenetics, the group strives to identify genetic biomarkers, enhance diagnostic accuracy, and optimize therapeutic strategies. Committed to excellence in research, the team aims to drive the development of personalized medicine and contribute to improved public health outcomes in Bangladesh and beyond.
MEMBER(S)
Identification of genetic marker for predicting resistance and toxicities of first-line antitubercular drugs
Tuberculosis (TB) remains one of the leading infectious diseases worldwide, and the emergence of drug-resistant strains poses a major challenge to effective treatment. The identification of genetic ma...
Identification of genetic markers in the severity of dengue disease in Bangladeshi population
Dengue is one of the most significant mosquito-borne viral diseases in Bangladesh, causing a wide range of clinical manifestations from mild fever to severe and life-threatening forms such as dengue h...
Effect of VDR gene polymorphisms on the autism in Bangladesh
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by difficulties in social interaction, communication, and repetitive behaviors. Although its exact cause remains ...
Identification of genetic markers in the insulin resistance in type2 DM patients of Bangladesh
Type 2 Diabetes Mellitus (T2DM) is a major public health problem in Bangladesh, characterized by chronic hyperglycemia resulting from insulin resistance and impaired insulin secretion. While lifestyle...
Identification of genetic marker to predict variation of methotrexate response in the patients with psoriasis
Psoriasis is a chronic, immune-mediated skin disorder characterized by excessive keratinocyte proliferation and inflammation. Methotrexate (MTX) is one of the most widely used and cost-effective syste...
: Effects of polymorphisms of HLA Class I and Class II genes on the variation of antibody production due to vaccination of COVID-19 in Bangladeshi population
The immune response to COVID-19 vaccination varies significantly among individuals, and genetic factors, particularly human leukocyte antigen (HLA) genes, play a crucial role in this variability. HLA ...
An investigation to identify the genetic variants associated with beta thalassemia in Bangladeshi population
Beta thalassemia is an inherited blood disorder caused by mutations in the HBB gene, leading to reduced or absent production of beta-globin chains in hemoglobin. This results in chronic anemia, ineffe...